Friday December 21, 2007



What is the difference between Renagel and Renvela ?

Sevelamer is indicated for the control of serum phosphorus (P) in patients with Chronic Kidney Disease on hemodialysis. Sevelamer controls phosphorus and "Ca x P product" without the concerns of metal accumulation.

Renagel and Renvela are two forms of Sevelamar.

Renagel is Sevelamar Hydrochloride while Renvela is the Sevelamar carbonate. Both tablets are produced by the same company and available in 800 mg forms.

Renvela, being in carbonate form has advantage as acid buffer and reduce the risk of acidosis. Renvela is a a next generation phosphate binder which will eventually replace Renagel (sevelamer hydrochloride).